287 ICRAV 2026 NOTES POSTER SESSION - SPEED PRESENTATION In contrast, the metabolite profile was quite plausible, since DHEA is converted to androstenedione, which can yield 6α-hydroxyandrostenedione, while androstenedione may also be hydroxylated to formestane (4-hydroxyandrostenedione), which is subsequently metabolized to 4-hydroxytestosterone. Unfortunately, as the supplement administered was no longer available for analysis, the possibility of the presence of an undeclared ingredient could not be ruled out. This case illustrates the challenges in equine anti-doping regulation. Case resolution depended on laboratory findings, international consultation and interdisciplinary collaboration. Subsequent international discussions underscored the importance of global scientific dialogue in equine anti-doping.
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